eBags via NeweggFlash offers its eBags Mother Lode TLS Mini 21" Wheeled Duffel in several colors (Blue Yonder pictured) for $149.99 with free shipping. That's the best deal today by $35 and the lowest price we've seen. It features a convertible single/double main compartment, 1.5" expansion zipper, multiple interior pockets, exterior zip pocket, locking telescoping trolley handle, retracting top lift handle, and two wheels.

Of note, eBags direct offers it in several additional colors for same price via coupon code "SPRING".